SCHEMBL15936147

SCHEMBL15936147

CCCS(=O)(=O)c1cc2[nH]c(-n3cc(OC(=O)O)cn3)nc2cc1C(F)(F)F

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16551726 0.90 EGLN1 (0.75) EGLN1
SCHEMBL16551749 0.88 EGLN1 (0.68) EGLN1
SCHEMBL15936117 0.88 EGLN1 (0.79) EGLN1
SCHEMBL1192576 0.86 EGLN1 (0.93) EGLN1
SCHEMBL16551393 0.86 EGLN1 (0.75) EGLN1
SCHEMBL15936200 0.86 EGLN1 (0.75) EGLN1
SCHEMBL15936082 0.86 EGLN1 (0.70) EGLN1
SCHEMBL16551712 0.84 EGLN1 (0.70) EGLN1
SCHEMBL16551699 0.81 EGLN1 (0.70) EGLN1
SCHEMBL16551674 0.81 EGLN1 (0.66) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294066-B9 BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-03-11 EP claimed
EP-2294066-B1 BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-13 EP claimed