SCHEMBL15936286

SCHEMBL15936286

O=C(CN1CCCCC1)Nc1cc2nc(-n3cc(OC(=O)O)cn3)[nH]c2cc1Cl

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15936184 0.92 EGLN1 (0.77) EGLN1
SCHEMBL15936146 0.92 EGLN1 (0.77) EGLN1
SCHEMBL1192640 0.87 EGLN1 (1.00) EGLN1
SCHEMBL16551687 0.87 EGLN1 (0.75) EGLN1
SCHEMBL16551704 0.84 EGLN1 (0.73) EGLN1
SCHEMBL16551208 0.82 EGLN1 (0.73) EGLN1
SCHEMBL16551650 0.81 EGLN1 (0.74) EGLN1
SCHEMBL16551711 0.80 EGLN1 (0.76) EGLN1
SCHEMBL16551600 0.80 EGLN1 (0.74) EGLN1
SCHEMBL16026853 0.80 EGLN1 (0.68) EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294066-B9 BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-03-11 EP claimed
EP-2294066-B1 BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-13 EP claimed