Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 18/20 | 0.82 |
| ▸ | ALOX5AP | P20292 | 18/20 | 0.82 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15917334 | 0.90 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL15917333 | 0.90 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL15916847 | 0.89 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL20627528 | 0.89 | FEN1 (0.83) | FEN1ALOX5AP | |
| SCHEMBL15916845 | 0.89 | ALOX5AP (0.79) | FEN1ALOX5AP | |
| SCHEMBL15916003 | 0.88 | FEN1 (0.76) | FEN1ALOX5AP | |
| SCHEMBL20627531 | 0.88 | FEN1 (0.76) | FEN1ALOX5AP | |
| SCHEMBL15916006 | 0.88 | FEN1 (0.76) | FEN1ALOX5AP | |
| SCHEMBL15915577 | 0.84 | FEN1 (1.00) | FEN1ALOX5AP | |
| SCHEMBL15915863 | 0.83 | FEN1 (1.00) | FEN1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |
| EP-3070085-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-09 | — | — | EP | disclosed |
| EP-3070085-A1 | FLAP MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2016-09-21 | — | — | EP | disclosed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | disclosed |