SCHEMBL15936747

SCHEMBL15936747

CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(C(N)=O)c(F)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.62
FEN1 P39748 19/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15916565 0.89 ALOX5AP (0.60) ALOX5APFEN1
SCHEMBL7994136 0.83 ALOX5AP (0.54) ALOX5APFEN1
SCHEMBL3546205 0.82 ALOX5AP (0.69) ALOX5APFEN1
SCHEMBL9122272 0.82 ALOX5AP (0.65) ALOX5APFEN1
SCHEMBL15916277 0.80 ALOX5AP (0.61) ALOX5APFEN1
SCHEMBL15915740 0.80 ALOX5AP (0.65) ALOX5APFEN1
SCHEMBL7994138 0.80 ALOX5AP (0.51) ALOX5APFEN1
SCHEMBL7130070 0.78 ALOX5AP (0.55) ALOX5APFEN1
SCHEMBL15917089 0.77 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL9118640 0.77 ALOX5AP (0.58) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014121055-A2 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-07 WO disclosed