Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2278798 | 0.89 | CA12 (0.71) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL12317800 | 0.86 | CA12 (0.62) | RAB9ANPC1SMN1; SMN2TP53CA12 | |
| SCHEMBL12317844 | 0.81 | CA12 (0.56) | RAB9ANPC1TP53CA12CA1 | |
| SCHEMBL12317679 | 0.81 | CA1 (0.56) | RAB9ANPC1SMN1; SMN2TP53CA12 | |
| SCHEMBL12317635 | 0.81 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL15937374 | 0.80 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL12317843 | 0.79 | CA1 (0.60) | RAB9ANPC1SMN1; SMN2TP53CA12 | |
| SCHEMBL12317682 | 0.79 | CA1 (0.60) | RAB9ANPC1SMN1; SMN2ALDH1A1CA12 | |
| SCHEMBL12317775 | 0.79 | CA1 (0.60) | RAB9ANPC1SMN1; SMN2CA12CA1 | |
| SCHEMBL12318064 | 0.79 | NPC1 (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2021-11-02 | — | — | US | disclosed |
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2020-08-06 | — | — | US | disclosed |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2019-05-09 | — | — | US | disclosed |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, LLC | 2018-03-08 | — | — | US | disclosed |
| WO-2014121124-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247828-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | RAB9A 627/4885NPC1 216/4885SMN1; SMN2 3037/4885 |
| US-11161858-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | RAB9A 627/4885NPC1 216/4885SMN1; SMN2 3037/4885 |
| US-20180065994-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | RAB9A 627/4885NPC1 216/4885SMN1; SMN2 3037/4885 |
| US-20190135837-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | RAB9A 627/4885NPC1 216/4885SMN1; SMN2 3037/4885 |
| US-10669291-B2 | Boron-containing small molecules as antiprotozoal agents | BTD, BAD, BRI3BP | RAB9A 627/4885NPC1 216/4885SMN1; SMN2 3037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.