Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594113 | 0.99 | NR1H2 (1.00) | NR1H2NR1H3 | |
| SCHEMBL1594805 | 0.97 | NR1H2 (0.95) | NR1H2NR1H3 | |
| SCHEMBL1595221 | 0.95 | NR1H2 (0.91) | NR1H2NR1H3 | |
| SCHEMBL1594603 | 0.93 | NR1H2 (0.88) | NR1H2NR1H3 | |
| SCHEMBL12705973 | 0.92 | NR1H2 (0.87) | NR1H2NR1H3 | |
| SCHEMBL1595249 | 0.92 | NR1H2 (0.87) | NR1H2NR1H3 | |
| SCHEMBL1595048 | 0.92 | NR1H2 (0.87) | NR1H2NR1H3 | |
| SCHEMBL1595171 | 0.92 | NR1H2 (0.86) | NR1H2NR1H3 | |
| SCHEMBL1595143 | 0.92 | NR1H2 (0.86) | NR1H2NR1H3 | |
| SCHEMBL1595486 | 0.92 | NR1H2 (0.86) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248811-B1 | 2-OXOCHROMENE DERIVATIVE | KOWA CO (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-7919509-B2 | 2-oxochromene derivatives | KOWA COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7919509-B2 | 2-oxochromene derivatives | KOWA COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7919509-B2 | 2-oxochromene derivatives | KOWA COMPANY, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| EP-2248811-A1 | 2-OXOCHROMENE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-20090286780-A1 | 2-OXOCHROMENE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286780-A1 | 2-OXOCHROMENE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286780-A1 | 2-OXOCHROMENE DERIVATIVES | KOWA COMPANY, LTD. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286780-A1 | 2-OXOCHROMENE DERIVATIVES | NR1H2, NR1H3, CYP46A1 | NR1H2 1/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.