Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681472 | 0.81 | KMT2A (0.52) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL15939815 | 0.77 | KMT2A (0.37) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL8654255 | 0.75 | POLB (0.57) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL11823665 | 0.73 | KMT2A (0.83) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL28681477 | 0.73 | KMT2A (0.52) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL28190202 | 0.73 | KMT2A (0.52) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL27559710 | 0.73 | KMT2A (0.68) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL5740698 | 0.73 | KMT2A (0.56) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL27586950 | 0.73 | KMT2A (0.47) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL19883160 | 0.73 | KMT2A (0.43) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10004232-B2 | Piperidine pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-06-26 | — | — | US | claimed |
| US-10004232-B2 | Piperidine pyrazoles as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| EP-2755971-B1 | PIPERIDINE PYRAZOLES AS FUNGICIDES | BAYER IP GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20140228404-A1 | PIPERIDINE PYRAZOLES AS FUNGICIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004232-B2 | Piperidine pyrazoles as fungicides | CAT, PIR, CYP51A1 | KMT2A 1490/4885HTT 497/4885SMN1; SMN2 4350/4885 |
| US-20140228404-A1 | PIPERIDINE PYRAZOLES AS FUNGICIDES | CAT, PIR, PIK3C3 | KMT2A 1005/4885HTT 197/4885SMN1; SMN2 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.