SCHEMBL1594032

SCHEMBL1594032

CC(Cl)OC(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.59
TP53 P04637 1/20 0.59
PDCD1 Q15116 1/20 0.56
CD274 Q9NZQ7 1/20 0.56
LMNA P02545 4/20 0.53
NPC1 O15118 3/20 0.53
ALDH1A1 P00352 3/20 0.53
HTT P42858 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 1/20 0.52
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
POLB P06746 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27610990 1.00 TSHR (0.59) TSHRTP53PDCD1CD274LMNA
SCHEMBL5672629 1.00 TSHR (0.59) TSHRTP53PDCD1CD274LMNA
SCHEMBL14689972 0.84 TSHR (0.55) TSHRTP53PDCD1CD274LMNA
SCHEMBL1965622 0.84 TSHR (0.55) TSHRTP53PDCD1CD274LMNA
SCHEMBL17965833 0.84 TSHR (0.55) TSHRTP53PDCD1CD274LMNA
SCHEMBL10239104 0.83 TSHR (0.63) TSHRTP53PDCD1CD274LMNA
SCHEMBL6660758 0.83 TSHR (0.63) TSHRTP53PDCD1CD274LMNA
SCHEMBL13625602 0.83 TSHR (0.63) TSHRTP53PDCD1CD274LMNA
SCHEMBL13700339 0.83 TSHR (0.63) TSHRTP53PDCD1CD274LMNA
Benzoic Acid 1-Methylethyl Ester SCHEMBL96918 0.83 PDCD1 (0.78) TSHRTP53PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070276-A Prodrugs of xanomeline, prodrugs of trospium chloride and methods of using the same 人类生物科学股份有限公司 2026-05-19 CN disclosed
EP-4705289-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF Terran Biosciences Inc. (US) 2026-03-11 EP disclosed
WO-2024226691-A1 PRODRUGS OF XANOMELINE, PRODRUGS OF TROSPIUM AND METHODS OF USE THEREOF TERRAN BIOSCIENCES INC. (US) 2024-10-31 WO disclosed
CN-114773215-B Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-09-02 CN disclosed
CN-114773215-A Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-07-22 CN disclosed
CN-114773215-A Oil field oily sewage oil removing agent and preparation method and application thereof 山东科兴化工有限责任公司 2022-07-22 CN disclosed
US-10087328-B2 Compound having azo skeleton, pigment dispersant, pigment composition, pigment dispersion, and toner CANON KABUSHIKI KAISHA (JP) 2018-10-02 US disclosed
EP-3001839-B1 COMPOUND HAVING AZO SKELETON, PIGMENT DISPERSANT, PIGMENT COMPOSITION, PIGMENT DISPERSION, AND TONER CANON KK (JP) 2018-07-18 EP disclosed
CN-107879935-A Method for synthesizing vinyl carboxylate 王建华 2018-04-06 CN disclosed
US-9834683-B2 Compound having azo skeleton structure, pigment dispersant, pigment composition, pigment dispersion, and toner CANON KABUSHIKI KAISHA (JP) 2017-12-05 US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 EP disclosed
CN-1060094-A Heterogeneous ring compound GLAXO SPA (IT) 1992-04-08 CN disclosed
EP-0475206-A2 Angiotensin II receptor antagonists ABBOTT LABORATORIES (US) 1992-03-18 EP disclosed
WO-1991008195-A1 N-(1-(2-CARBOXYETHYL)CYCLOALKYL CARBONYL)-BETA-ALANINE DERIVATIVES FOR PHARMACEUTICAL USE PFIZER LIMITED (GB) 1991-06-13 WO disclosed
US-4900478-A SKIN DISORDERS HOFFMANN-LA ROCHE INC. (US) 1990-02-13 US disclosed
EP-0147177-B1 ETHER PRODRUGS OF ANTI-INFLAMMATORY OXICAMS PFIZER INC. (US) 1987-10-14 EP disclosed
US-4551452-A Anti-inflammatory 2-methyl-2H-1,2-benzo-(or -thieno-)thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor PFIZER INC. (US) 1985-11-05 US disclosed
EP-0147177-A2 Ether prodrugs of anti-inflammatory oxicams PFIZER INC. (US) 1985-07-03 EP disclosed
US-4456465-A HERBICIDES ZOECON CORPORATION (US) 1984-06-26 US disclosed
US-RE28850-E Process for preparing alternating copolymer of butadiene and α-olefine and novel alternating copolymer of butadiene and α-olefine containing cis-configuration butadiene unit MARUZEN PETROCHEMICAL CO., LTD. (JA) 1976-06-08 US disclosed