SCHEMBL15944480

SCHEMBL15944480

CC(C)[SiH2]C#Cc1c2cc3ccccc3cc2c(C#C[SiH2]C(C)C)c2cc3ccccc3cc12

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
UGT2B7 P16662 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HIF1A Q16665 1/20 0.30
CYP1B1 Q16678 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18998896 0.87 CACNA2D1 (0.30)
SCHEMBL652531 0.86 NQO1 (0.32) NQO1HTR2AHTR2CHTR2BUGT2B7
SCHEMBL648823 0.82 CYP1A2 (0.36) NQO1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL28541936 0.81
SCHEMBL651705 0.80
SCHEMBL650878 0.80 CYP1A2 (0.34) NQO1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL652960 0.79
SCHEMBL649326 0.77 NQO1 (0.35) NQO1HTR2AHTR2CHTR2BUGT2B7
SCHEMBL649817 0.77 CYP1A2 (0.33) HTR2ACYP1A2CYP2A6CYP1B1
SCHEMBL650998 0.76 NQO1 (0.31) NQO1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170141332-A1 ORGANIC TRANSISTOR CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-05-18 US disclosed
US-9373795-B2 Organic semiconductor composition including a non-polymeric material having a polydispersity equal to one, at least one solvent, and a crystallization modifier, and an organic thin-film transistor using the same CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-06-21 US disclosed
US-9231219-B2 N-doping of organic semiconductors by bis-metallosandwich compounds GEORGIA TECH RESEARCH CORPORATION (US) 2016-01-05 US disclosed
US-20140353647-A1 Organic Thin Film Transistors And Method of Making Them CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-12-04 US disclosed
US-20140299869-A1 Organic Electronic Device And Method Of Manufacture CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-10-09 US disclosed
US-20140302635-A1 N-DOPING OF ORGANIC SEMICONDUCTORS BY BIS-METALLOSANDWICH COMPOUNDS THE TRUSTEES OF PRINCETON UNIVERSITY 2014-10-09 US disclosed
US-20140225101-A1 Organic Semiconductor Composition And Organic Transistor CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-08-14 US disclosed