SCHEMBL15945858

SCHEMBL15945858

N#Cc1cc(-c2cc(-n3c4ccccc4c4ccccc43)cc(-n3c4ccccc4c4ccccc43)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PTGER4 P35408 1/20 0.38
PGR P06401 2/20 0.37
RXFP1 Q9HBX9 1/20 0.35
IMPDH2 P12268 1/20 0.34
METAP2 P50579 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
TSHR P16473 1/20 0.33
CYP19A1 P11511 1/20 0.33
USP14 P54578 1/20 0.33
ADORA2A P29274 1/20 0.33
RORC P51449 1/20 0.32
ENPP3 O14638 1/20 0.32
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18574642 0.98 KDM4E (0.47) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18874148 0.97 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL29457609 0.97 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL30570321 0.93 KDM4E (0.52) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL8282719 0.93 KDM4E (0.52) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL30968746 0.93 KDM4E (0.52) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL18715204 0.92 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL17721935 0.92 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18715205 0.92 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL18715076 0.92 KDM4E (0.46) KDM4EATML3MBTL1PTGER4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed