Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822272 | 1.00 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1MAT2A | |
| SCHEMBL20199512 | 0.99 | KDM4E (0.46) | KDM4EATML3MBTL1PTPN1MAT2A | |
| SCHEMBL20203650 | 0.96 | KDM4E (0.44) | KDM4EATML3MBTL1 | |
| SCHEMBL15946311 | 0.95 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1HDAC4 | |
| SCHEMBL14822433 | 0.95 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1HDAC4 | |
| SCHEMBL15946331 | 0.95 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1HDAC4 | |
| SCHEMBL14822252 | 0.95 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1HDAC4 | |
| SCHEMBL16373497 | 0.95 | KDM4E (0.47) | KDM4EATML3MBTL1PTPN1MAT2A | |
| SCHEMBL23058894 | 0.95 | KDM4E (0.53) | KDM4EATML3MBTL1PTPN1HDAC4 | |
| SCHEMBL20129527 | 0.95 | KDM4E (0.53) | KDM4EATML3MBTL1PTPN1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |