Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11491143 | 0.97 | MAOB (0.65) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL11491145 | 0.97 | MAOB (0.65) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL7040103 | 0.87 | HDAC6 (0.78) | KDM4EALDH1A1MAOBSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL27627702 | 0.86 | HDAC6 (0.76) | KDM4EALDH1A1MAOBSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL27337301 | 0.86 | HDAC6 (0.76) | KDM4EALDH1A1MAOBSMN1; SMN2RAB9A | |
| SCHEMBL12809923 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27276199 | 0.85 | HDAC6 (0.74) | KDM4EALDH1A1MAOBSMN1; SMN2RAB9A | |
| SCHEMBL14882065 | 0.84 | HDAC6 (0.81) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL14882066 | 0.84 | HDAC6 (0.81) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 | |
| SCHEMBL31345022 | 0.82 | MAOB (0.64) | KDM4EALDH1A1MAPTMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614046-B1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) | 2014-08-20 | — | — | EP | disclosed |