Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660342 | 0.96 | FFAR1 (0.48) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL1802536 | 0.96 | FFAR1 (0.48) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL1892518 | 0.90 | FFAR1 (0.47) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL1892708 | 0.86 | FFAR1 (0.52) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL1888903 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL16863743 | 0.85 | FFAR1 (0.51) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL38659420 | 0.84 | FFAR1 (0.50) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL1811354 | 0.84 | FFAR1 (0.50) | FFAR1FFAR4PTGER4PTGER3PTGER1 | |
| SCHEMBL38660429 | 0.83 | CYP4F2 (0.39) | FFAR1FFAR4LDHALDHBPDE1A | |
| SCHEMBL1888603 | 0.83 | CYP4F2 (0.39) | FFAR1FFAR4LDHALDHBPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496544-B1 | GPBP INHIBITION USING Q2 PEPTIDOMIMETICS | FIBROSTATIN S L (SE) | 2014-08-20 | — | — | EP | claimed |