Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.52 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 3/20 | 0.33 |
| ▸ | CCL5 | P13501 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390522 | 1.00 | GPBAR1 (0.52) | GPBAR1PROKR1NR3C2PRCPPRMT5 | |
| SCHEMBL369619 | 0.93 | GPBAR1 (0.52) | GPBAR1PROKR1NR3C2PRCPCTSA | |
| SCHEMBL369620 | 0.93 | GPBAR1 (0.52) | GPBAR1PROKR1NR3C2PRCPCTSA | |
| SCHEMBL1390981 | 0.91 | GPBAR1 (0.55) | GPBAR1PROKR1PRCPTLR8TLR7 | |
| SCHEMBL363414 | 0.91 | GPBAR1 (0.55) | GPBAR1PROKR1PRCPTLR8TLR7 | |
| SCHEMBL1390337 | 0.89 | GPBAR1 (0.64) | GPBAR1PROKR1NR3C2PRCPPRMT5 | |
| SCHEMBL1390336 | 0.89 | GPBAR1 (0.64) | GPBAR1PROKR1NR3C2PRCPPRMT5 | |
| SCHEMBL1390339 | 0.89 | GPBAR1 (0.64) | GPBAR1PROKR1NR3C2PRCPPRMT5 | |
| SCHEMBL1390338 | 0.89 | GPBAR1 (0.64) | GPBAR1PROKR1NR3C2PRCPPRMT5 | |
| SCHEMBL370093 | 0.88 | GPBAR1 (0.52) | GPBAR1PROKR1NR3C2PRCPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |