Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.49 |
| ▸ | CTSA | P10619 | 8/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949092 | 0.88 | GPBAR1 (0.62) | GPBAR1CTSAHDAC4 | |
| SCHEMBL15949094 | 0.88 | GPBAR1 (0.62) | GPBAR1CTSAHDAC4 | |
| SCHEMBL15949109 | 0.87 | HPGD (0.46) | GPBAR1HDAC4PLOD2PLOD3ALDH1A1 | |
| SCHEMBL15949134 | 0.86 | GPBAR1 (0.45) | GPBAR1CTSAHDAC4 | |
| SCHEMBL363379 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAHDAC4GAA | |
| SCHEMBL363055 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAHDAC4GAA | |
| SCHEMBL362335 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAHDAC4GAA | |
| SCHEMBL15949055 | 0.84 | GPBAR1 (0.48) | GPBAR1CTSAMGAMGAASI | |
| SCHEMBL363384 | 0.83 | MGAM (0.51) | GPBAR1MGAMGAASIMGAM2 | |
| SCHEMBL361906 | 0.81 | GPBAR1 (0.57) | GPBAR1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |