Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.62 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | ADH5 | P11766 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FABP2 | P12104 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364387 | 0.91 | GPBAR1 (0.54) | GPBAR1FAAHCTSAFFAR1LMNA | |
| SCHEMBL363345 | 0.89 | GPBAR1 (0.80) | GPBAR1FAAHCTSARARBADH5 | |
| SCHEMBL10240968 | 0.89 | GPBAR1 (0.80) | GPBAR1FAAHCTSARARBADH5 | |
| SCHEMBL1389929 | 0.89 | GPBAR1 (0.80) | GPBAR1FAAHCTSARARBADH5 | |
| SCHEMBL362812 | 0.88 | GPBAR1 (0.78) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL363310 | 0.88 | GPBAR1 (0.78) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL365538 | 0.88 | GPBAR1 (0.78) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL364037 | 0.87 | GPBAR1 (0.72) | GPBAR1CTSANR3C2 | |
| SCHEMBL363087 | 0.87 | GPBAR1 (0.72) | GPBAR1CTSANR3C2 | |
| SCHEMBL362655 | 0.84 | GPBAR1 (0.61) | GPBAR1CTSAPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |