Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.35 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948981 | 0.89 | GPBAR1 (0.51) | GPBAR1L3MBTL1MGAMGAASI | |
| SCHEMBL15948980 | 0.89 | GPBAR1 (0.51) | GPBAR1L3MBTL1MGAMGAASI | |
| SCHEMBL1389539 | 0.87 | GPBAR1 (0.59) | GPBAR1L3MBTL1NPSR1CFTRCTSA | |
| SCHEMBL1389537 | 0.87 | GPBAR1 (0.59) | GPBAR1L3MBTL1NPSR1CFTRCTSA | |
| SCHEMBL362837 | 0.87 | GPBAR1 (0.59) | GPBAR1L3MBTL1NPSR1CFTRCTSA | |
| SCHEMBL361906 | 0.85 | GPBAR1 (0.57) | GPBAR1L3MBTL1POLBHTTNPSR1 | |
| SCHEMBL15949181 | 0.81 | CNR2 (0.47) | GPBAR1L3MBTL1POLBHTTNPSR1 | |
| SCHEMBL363384 | 0.78 | MGAM (0.51) | GPBAR1L3MBTL1POLBHTTNPSR1 | |
| SCHEMBL1389969 | 0.78 | GPBAR1 (0.63) | GPBAR1L3MBTL1NPSR1CFTRCTSA | |
| SCHEMBL1389970 | 0.78 | GPBAR1 (0.63) | GPBAR1L3MBTL1NPSR1CFTRCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |