Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 5/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362327 | 0.91 | GPBAR1 (0.53) | GPBAR1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL363896 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL1390177 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL365323 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL1389809 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL1390182 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL1389807 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL1389810 | 0.90 | GPBAR1 (0.69) | GPBAR1NOTUMGPR6F10FFAR4 | |
| SCHEMBL362799 | 0.85 | GPBAR1 (0.50) | GPBAR1NOTUMKDM4EUSP2HPGD | |
| SCHEMBL362197 | 0.85 | GPBAR1 (0.50) | GPBAR1NOTUMKDM4EUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |