Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949065 | 1.00 | GPBAR1 (0.53) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL15948981 | 0.90 | GPBAR1 (0.51) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL15948980 | 0.90 | GPBAR1 (0.51) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL1389855 | 0.87 | GPBAR1 (0.66) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL1389846 | 0.87 | GPBAR1 (0.66) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL1389851 | 0.87 | GPBAR1 (0.66) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL1389853 | 0.87 | GPBAR1 (0.66) | GPBAR1L3MBTL1NR3C2KDM4AKDM4C | |
| SCHEMBL1390447 | 0.85 | GPBAR1 (0.62) | GPBAR1NR3C2CTSAGAAMGAM | |
| SCHEMBL1390446 | 0.85 | GPBAR1 (0.62) | GPBAR1NR3C2CTSAGAAMGAM | |
| SCHEMBL365241 | 0.84 | GPBAR1 (0.59) | GPBAR1NR3C2CTSAGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |