Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370968 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL362667 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL363946 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL1389951 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL363003 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL1390008 | 1.00 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL1390482 | 0.95 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL364010 | 0.95 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL1389712 | 0.95 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 | |
| SCHEMBL364252 | 0.95 | GPBAR1 (0.58) | GPBAR1ADRB1ADRB3PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |