Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MGAM | O43451 | 3/20 | 0.43 |
| ▸ | SI | P14410 | 3/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1390407 | 0.89 | GPBAR1 (0.50) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL368424 | 0.89 | GPBAR1 (0.48) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL369990 | 0.87 | GPBAR1 (0.48) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL371067 | 0.87 | GPBAR1 (0.46) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL1390266 | 0.87 | GPBAR1 (0.48) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL369140 | 0.87 | GPBAR1 (0.54) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL369733 | 0.87 | GPBAR1 (0.54) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL369139 | 0.87 | GPBAR1 (0.54) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL369091 | 0.87 | GPBAR1 (0.62) | GPBAR1GAAMGAMSIMGAM2 | |
| SCHEMBL370700 | 0.87 | GPBAR1 (0.62) | GPBAR1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |