Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.53 |
| ▸ | CTSA | P10619 | 11/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389819 | 0.87 | GPBAR1 (0.69) | GPBAR1CTSAKMO | |
| SCHEMBL362770 | 0.87 | GPBAR1 (0.69) | GPBAR1CTSAKMO | |
| SCHEMBL1389844 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAKMO | |
| SCHEMBL1389847 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAKMO | |
| SCHEMBL364258 | 0.85 | GPBAR1 (0.61) | GPBAR1CTSAKMO | |
| SCHEMBL362998 | 0.85 | GPBAR1 (0.56) | GPBAR1CTSA | |
| SCHEMBL370704 | 0.85 | GPBAR1 (0.56) | GPBAR1CTSA | |
| SCHEMBL1390482 | 0.84 | GPBAR1 (0.58) | GPBAR1KMO | |
| SCHEMBL1390008 | 0.84 | GPBAR1 (0.58) | GPBAR1 | |
| SCHEMBL364010 | 0.84 | GPBAR1 (0.58) | GPBAR1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |