Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.78 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 10/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949128 | 1.00 | GPBAR1 (0.78) | GPBAR1NR3C2CTSASRC | |
| SCHEMBL15949210 | 1.00 | GPBAR1 (0.78) | GPBAR1NR3C2CTSASRC | |
| SCHEMBL15949127 | 1.00 | GPBAR1 (0.78) | GPBAR1NR3C2CTSASRC | |
| SCHEMBL10240982 | 0.91 | GPBAR1 (0.94) | GPBAR1NR3C2CTSA | |
| SCHEMBL1389693 | 0.91 | GPBAR1 (0.94) | GPBAR1NR3C2CTSA | |
| SCHEMBL364915 | 0.91 | GPBAR1 (0.94) | GPBAR1NR3C2CTSA | |
| SCHEMBL361887 | 0.91 | GPBAR1 (0.94) | GPBAR1NR3C2CTSA | |
| SCHEMBL363423 | 0.91 | GPBAR1 (0.94) | GPBAR1NR3C2CTSA | |
| SCHEMBL1389749 | 0.90 | GPBAR1 (0.78) | GPBAR1NR3C2CTSA | |
| SCHEMBL1389746 | 0.90 | GPBAR1 (0.78) | GPBAR1NR3C2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |