Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | GPR6 | P46095 | 6/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949197 | 1.00 | GPBAR1 (0.65) | GPBAR1HRH3ACACBGPR6KDM5A | |
| SCHEMBL1389809 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL1390177 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL365323 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL1389810 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL1390182 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL363896 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL1389807 | 0.91 | GPBAR1 (0.69) | GPBAR1GPR6F10 | |
| SCHEMBL1390414 | 0.89 | GPBAR1 (0.65) | GPBAR1 | |
| SCHEMBL364437 | 0.89 | GPBAR1 (0.65) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |