Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.59 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 7/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949317 | 0.92 | GPBAR1 (0.62) | GPBAR1CTSAACACBMAPTMEN1 | |
| SCHEMBL15949212 | 0.92 | GPBAR1 (0.62) | GPBAR1CTSAACACBMAPTMEN1 | |
| SCHEMBL1390149 | 0.90 | GPBAR1 (0.61) | GPBAR1MAPTTP53KDM4EMEN1 | |
| SCHEMBL363177 | 0.90 | GPBAR1 (0.61) | GPBAR1MAPTTP53KDM4EMEN1 | |
| SCHEMBL1389955 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A | |
| SCHEMBL1389953 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A | |
| SCHEMBL1389958 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A | |
| SCHEMBL1389739 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A | |
| SCHEMBL364189 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A | |
| SCHEMBL362777 | 0.86 | GPBAR1 (0.65) | GPBAR1CTSAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | claimed |