Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15834432 | 0.92 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15958203 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957621 | 0.89 | MAPK1 (0.43) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957626 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957614 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957877 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL17287107 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957878 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL15957875 | 0.82 | RXRB (0.41) | SMN1; SMN2MEN1KMT2AHSD17B10ALOX15 | |
| SCHEMBL15957891 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809451-B2 | Fluorinated dicarboxylic acid derivative and polymer obtained therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-08-19 | — | — | US | disclosed |
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | CENTRAL GLASS COMPANY, LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301305-A1 | Fluorinated Dicarboxylic Acid Derivative and Polymer Obtained Therefrom | MCCC2, AFF2, F13A1 | SMN1; SMN2 3546/4885MEN1 1359/4885KMT2A 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.