Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.57 |
| ▸ | BCL2 | P10415 | 13/20 | 0.57 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9950663 | 0.94 | BCL2L1 (0.65) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9950665 | 0.94 | BCL2L1 (0.65) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9950580 | 0.93 | BCL2L1 (0.55) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9950579 | 0.93 | BCL2L1 (0.55) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9950922 | 0.84 | BCL2L1 (0.64) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9950915 | 0.84 | BCL2L1 (0.64) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9952377 | 0.84 | BCL2L1 (0.59) | BCL2L1BCL2 | |
| SCHEMBL9952374 | 0.84 | BCL2L1 (0.59) | BCL2L1BCL2 | |
| SCHEMBL15958422 | 0.83 | BCL2L1 (0.54) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL9952190 | 0.82 | BCL2L1 (0.55) | BCL2L1BCL2BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809352-B2 | Sulfonamides as inhibitors of Bcl-2 family proteins for the treatments of cancer | NOVARTIS AG (CH) | 2014-08-19 | — | — | US | disclosed |