Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 13/20 | 0.68 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13284991 | 0.88 | EHMT2 (0.67) | EHMT2NTRK1MAPTMEN1APP | |
| SCHEMBL2483882 | 0.88 | EHMT2 (0.71) | EHMT2NTRK1MAPTMEN1APP | |
| SCHEMBL2483448 | 0.84 | EHMT2 (0.61) | EHMT2NTRK1MAPTMEN1APP | |
| SCHEMBL13285003 | 0.78 | EHMT2 (0.73) | EHMT2NTRK1MAPTMEN1APP | |
| SCHEMBL13284988 | 0.78 | EHMT2 (0.68) | EHMT2MAPTMEN1APPTHRB | |
| SCHEMBL17874500 | 0.77 | PLAU (0.81) | EHMT2NTRK1MAPTPLAUPLAUR | |
| SCHEMBL13284990 | 0.76 | EHMT2 (0.67) | EHMT2NTRK1MAPTMEN1APP | |
| SCHEMBL15077931 | 0.74 | EHMT2 (0.64) | EHMT2NTRK1MAPTPLAUPLAUR | |
| SCHEMBL16978027 | 0.74 | NTRK1 (0.81) | EHMT2NTRK1MAPTTHRBPLAU | |
| SCHEMBL13285004 | 0.74 | NTRK1 (0.62) | EHMT2NTRK1MAPTMEN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809530-B1 | Compositions of protein receptor tyrosine kinase inhibitors | VM PHARMA LLC (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809530-B1 | Compositions of protein receptor tyrosine kinase inhibitors | VM PHARMA LLC (US) | 2014-08-19 | — | — | US | disclosed |