Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595022 | 0.86 | KDM4E (0.53) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL12669858 | 0.84 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL14191220 | 0.84 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL8141827 | 0.76 | HRH4 (0.52) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL14218356 | 0.76 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL15958611 | 0.75 | KDM4E (0.63) | MEN1KMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL15958630 | 0.74 | APP (0.52) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10844115 | 0.73 | KDM4E (0.49) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL15958613 | 0.72 | KDM4E (0.44) | MEN1KMT2ASMN1; SMN2MAPTRAB9A | |
| SCHEMBL7474377 | 0.71 | NQO2 (0.56) | MEN1KMT2ASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809264-B2 | Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | disclosed |