SCHEMBL15958848

SCHEMBL15958848

O=C1C2C3C=CC(C3)C2C(=O)N1CCCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 1.00
TSHR P16473 2/20 1.00
USP2 O75604 1/20 1.00
HSD17B10 Q99714 1/20 1.00
ALDH1A1 P00352 7/20 0.79
RAB9A P51151 2/20 0.77
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
MAPK1 P28482 1/20 0.63
KDM4E B2RXH2 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
LMNA P02545 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597717 1.00 HTT (1.00) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL31141363 0.95 HTT (0.90) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL29249606 0.93 HTT (0.87) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL20546502 0.93 HTT (0.87) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL28740189 0.93 HTT (0.87) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL15967771 0.93 HTT (0.87) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL19387118 0.89 HTT (0.80) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL22279732 0.89 HTT (0.80) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL15967718 0.89 HTT (0.80) HTTTSHRUSP2HSD17B10ALDH1A1
SCHEMBL10731583 0.89 HTT (0.80) HTTTSHRUSP2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399457-A1 Bioactive Synthetic Copolymer, Bioactive Macromolecule and Related Methods Thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-12-14 US disclosed
WO-2023211384-A1 HYALURONIC ACID-BASED SYNTHETIC COPOLYMER, MATERIAL CONTAINING SAID COPOLYMER AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-11-02 WO disclosed
WO-2022093106-A1 BIOACTIVE SYNTHETIC COPOLYMER, BIOACTIVE MACROMOLECULE AND RELATED METHODS THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2022-05-05 WO disclosed
US-20180201723-A1 POLYMER BASED MEMRISTORS THE UNIVERSITY OF WESTERN ONTARIO (CA) 2018-07-19 US disclosed
US-20180201723-A1 POLYMER BASED MEMRISTORS THE UNIVERSITY OF WESTERN ONTARIO (CA) 2018-07-19 US disclosed
US-8809466-B2 Degradable polymers, methods of making the same, and uses thereof THE UNIVERSITY OF SOUTH CAROLINA (US) 2014-08-19 US disclosed