Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.68 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363213 | 0.90 | GPBAR1 (0.73) | GPBAR1 | |
| SCHEMBL1389756 | 0.90 | GPBAR1 (0.73) | GPBAR1 | |
| SCHEMBL10240959 | 0.90 | GPBAR1 (0.73) | GPBAR1 | |
| SCHEMBL363572 | 0.87 | GPBAR1 (0.86) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL10240962 | 0.87 | GPBAR1 (0.86) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1389562 | 0.87 | GPBAR1 (0.86) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL15949206 | 0.84 | GPBAR1 (0.70) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1390003 | 0.83 | GPBAR1 (0.72) | GPBAR1CTSA | |
| SCHEMBL1390001 | 0.83 | GPBAR1 (0.72) | GPBAR1CTSA | |
| SCHEMBL1390004 | 0.83 | GPBAR1 (0.72) | GPBAR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |