Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.68 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.68 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.68 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.68 |
| ▸ | THRB | P10828 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999794 | 1.00 | MAPT (1.00) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28026504 | 0.83 | MAPT (0.70) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1557957 | 0.81 | GRIN2D (1.00) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6021110 | 0.81 | GRIN2D (1.00) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL167788 | 0.81 | GRIN2D (1.00) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9003838 | 0.81 | MAPT (0.68) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2043404 | 0.78 | MAPT (0.64) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15903721 | 0.78 | MAPT (0.64) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28341616 | 0.77 | MAPT (0.63) | MAPTGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6577891 | 0.77 | MAPT (0.63) | MAPTGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114244359-B | Calibration method and calibration module of analog-to-digital converter and analog-to-digital converter | 厦门半导体工业技术研发有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-114244359-A | Calibration method and calibration module of analog-to-digital converter and analog-to-digital converter | 厦门半导体工业技术研发有限公司 | 2022-03-25 | — | — | CN | disclosed |
| US-20140235576-A1 | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS IGLUR ANTAGONISTS | KOBENHAVNS UNIVERSITET (DK) | 2014-08-21 | — | — | US | disclosed |
| US-20140235576-A1 | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS IGLUR ANTAGONISTS | KOBENHAVNS UNIVERSITET (DK) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235576-A1 | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AS IGLUR ANTAGONISTS | GRIK2, GABRE, GRIK5 | MAPT 72/4885GRIN2D 34/4885GRIN3B 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.