SCHEMBL15965698

SCHEMBL15965698

c1ccc2c(c1)oc1cc(-c3ccc4oc5ccc(-n6c7ccccc7c7ccccc76)cc5c4c3)c(-c3ccc4oc5ccc(-n6c7ccccc7c7ccccc76)cc5c4c3)cc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
AHR P35869 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 1/20 0.41
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
ALOX5 P09917 1/20 0.36
PGR P06401 1/20 0.36
PTGER4 P35408 1/20 0.35
CHEK2 O96017 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15965685 0.93 KDM4E (0.41) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL9890255 0.93 KDM4E (0.40) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL9890516 0.92 KDM4E (0.39) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL9890075 0.92 MAPT (0.42) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL10348589 0.91 KDM4E (0.45) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL15780988 0.91 KDM4E (0.45) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL15965683 0.90 KDM4E (0.40) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL15965684 0.90 KDM4E (0.40) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL15965739 0.90 KDM4E (0.40) MAPTKDM4EMEN1KMT2AAHR
SCHEMBL9890335 0.90 MAPT (0.41) MAPTKDM4EMEN1KMT2AAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed
US-20140231772-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 US disclosed