Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 8/20 | 0.85 |
| ▸ | HK2 | P52789 | 8/20 | 0.85 |
| ▸ | LGALS9 | O00182 | 2/20 | 0.66 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.66 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.66 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17766481 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL20202233 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL20202229 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL15965651 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL8773129 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL18390973 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL18390838 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL14520984 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL15965644 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 | |
| SCHEMBL15966253 | 1.00 | HK1 (0.85) | HK1HK2LGALS9LGALS1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170204444-A9 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-07-20 | — | — | US | disclosed |
| US-20170016040-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-19 | — | — | US | disclosed |
| US-9290530-B2 | Chemoenzymatic synthesis of heparin and heparan sulfate analogs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140235575-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235575-A1 | CHEMOENZYMATIC SYNTHESIS OF HEPARIN AND HEPARAN SULFATE ANALOGS | HPSE, ENGASE, GALE | HK1 51/4885HK2 111/4885LGALS9 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.