Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL167725 | 1.00 | — | — | |
| Acetic Acid SCHEMBL27972688 | 0.86 | — | — | |
| SCHEMBL7243571 | 0.82 | — | — | |
| Bicarbonate SCHEMBL26100283 | 0.79 | — | — | |
| Bicarbonate SCHEMBL165021 | 0.76 | — | — | |
| Bicarbonate SCHEMBL2782263 | 0.76 | — | — | |
| Bicarbonate SCHEMBL27963055 | 0.76 | CA1 (0.46) | CA1CA2CA9FFAR3LCK | |
| Urea SCHEMBL11071285 | 0.76 | — | — | |
| Bicarbonate SCHEMBL21598431 | 0.73 | — | — | |
| Bicarbonate SCHEMBL27942113 | 0.73 | CA1 (0.42) | CA1CA2CA9FFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2779299-B1 | NONAQUEOUS ELECTROLYTE SOLUTION, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY USING SAID ELECTROLYTE SOLUTION | ADEKA CORP (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9419306-B2 | Nonaqueous electrolyte and nonaqueous secondary battery using same | ADEKA CORPORATION (JP) | 2016-08-16 | — | — | US | disclosed |
| EP-2775559-B1 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY | ADEKA CORP (JP) | 2016-07-06 | — | — | EP | disclosed |
| US-9337511-B2 | Nonaqueous secondary battery | ADEKA CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150044551-A1 | NONAQUEOUS SECONDARY BATTERY | ADEKA CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2779299-A1 | NONAQUEOUS ELECTROLYTE SOLUTION, AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY USING SAID ELECTROLYTE SOLUTION | Adeka Corporation (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-2775559-A1 | NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY | Adeka Corporation (JP) | 2014-09-10 | — | — | EP | disclosed |
| US-20140242456-A1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY USING SAME | ADEKA CORPORATION (JP) | 2014-08-28 | — | — | US | disclosed |