Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18151306 | 0.84 | POLB (0.58) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL28362379 | 0.83 | TSHR (0.54) | NPSR1MAPTLMNANLRP3TSHR | |
| SCHEMBL15968923 | 0.82 | POLB (0.48) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL15969801 | 0.82 | POLB (0.49) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL312971 | 0.80 | POLB (0.48) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL15253446 | 0.80 | F2 (0.53) | NPSR1MEN1LMNAKMT2ATSHR | |
| SCHEMBL15970306 | 0.79 | POLB (0.44) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL14874588 | 0.76 | KMT2A (0.43) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL14874322 | 0.76 | KMT2A (0.43) | POLBHTTNPSR1L3MBTL1MAPT | |
| SCHEMBL18151122 | 0.76 | HTT (0.66) | POLBHTTNPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768873-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-11-22 | — | — | EP | disclosed |
| US-8921253-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-12-30 | — | — | US | disclosed |
| US-20140243490-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2014-08-28 | — | — | US | disclosed |