Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15970643 | 1.00 | KMT2A (0.72) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL27349411 | 0.83 | KMT2A (0.68) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL8954085 | 0.81 | KMT2A (0.69) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL8954080 | 0.81 | KMT2A (0.69) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL14375120 | 0.80 | HPGD (0.53) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL3885423 | 0.79 | HPGD (0.54) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL8976300 | 0.78 | MEN1 (0.61) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL8976297 | 0.78 | MEN1 (0.61) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL613703 | 0.78 | HPGD (0.51) | KMT2AMEN1HPGDPKMMAPK1 | |
| SCHEMBL4649558 | 0.78 | HPGD (0.56) | KMT2AMEN1HPGDPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014129874-A1 | PIPER AMIDE-BASED COMPOUND AS BOMBESIN RECEPTOR SUBTYPE 3 | 서울대학교산학협력단 (KR) | 2014-08-28 | — | — | WO | disclosed |