⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17368096 | 0.81 | — | — | |
| SCHEMBL15973524 | 0.79 | — | — | |
| SCHEMBL17363736 | 0.79 | — | — | |
| SCHEMBL15973526 | 0.79 | — | — | |
| SCHEMBL17363735 | 0.79 | — | — | |
| SCHEMBL19799251 | 0.78 | — | — | |
| SCHEMBL6663861 | 0.77 | GLB1 (0.30) | — | |
| SCHEMBL13683698 | 0.76 | — | — | |
| SCHEMBL3862579 | 0.76 | — | — | |
| SCHEMBL12292232 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958905-B1 | CARBOHYDRATE PHOSPHONATE DERIVATIVES AS MODULATORS OF GLYCOSYLATION | AMGEN INC (US) | 2017-03-29 | — | — | EP | disclosed |
| US-9328134-B2 | Carbohydrate phosphonate derivatives as modulators of glycosylation | AMGEN INC. (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150376221-A1 | Carbohydrate Phosphonate Derivatives as Modulators of Glycosylation | AMGEN INC. | 2015-12-31 | — | — | US | disclosed |
| EP-2958905-A2 | CARBOHYDRATE PHOSPHONATE DERIVATIVES AS MODULATORS OF GLYCOSYLATION | Amgen Inc. (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130613-A2 | CARBOHYDRATE PHOSPHONATE DERIVATIVES AS MODULATORS OF GLYCOSYLATION | AMGEN INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2014130613-A2 | CARBOHYDRATE PHOSPHONATE DERIVATIVES AS MODULATORS OF GLYCOSYLATION | AMGEN INC. (US) | 2014-08-28 | — | — | WO | disclosed |