Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975439 | 0.98 | HDAC4 (0.31) | HDAC4HDAC1 | |
| SCHEMBL15975444 | 0.96 | HDAC4 (0.31) | HDAC4HDAC1DPP8DPP9 | |
| SCHEMBL15975441 | 0.92 | — | — | |
| SCHEMBL15975442 | 0.90 | — | — | |
| SCHEMBL15976112 | 0.89 | HDAC4 (0.30) | HDAC4HDAC1 | |
| SCHEMBL15975438 | 0.89 | — | — | |
| SCHEMBL12401332 | 0.88 | CYP3A4 (0.34) | HDAC4HDAC1 | |
| SCHEMBL15976107 | 0.87 | — | — | |
| SCHEMBL15976111 | 0.86 | HDAC4 (0.30) | HDAC4HDAC1 | |
| SCHEMBL12401328 | 0.86 | CYP3A4 (0.34) | HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815796-B2 | Polyheterocyclic compounds highly potent as HCV inhibitors | AB Pharma Ltd. (CN) | 2014-08-26 | — | — | US | disclosed |