Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975472 | 1.00 | EPHX1 (0.75) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15975479 | 1.00 | EPHX1 (0.75) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10192072 | 0.94 | MEN1 (0.69) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL6438910 | 0.91 | EPHX1 (0.83) | EPHX1ALDH1A1HTTEPHX2MAPT | |
| SCHEMBL10192064 | 0.88 | MAPT (0.72) | EPHX1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL12196058 | 0.86 | EPHX1 (1.00) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8599536 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1HTTEPHX2MAPT | |
| SCHEMBL3157400 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1HTTEPHX2MAPT | |
| SCHEMBL12196036 | 0.86 | EPHX1 (1.00) | EPHX1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8601252 | 0.86 | EPHX1 (0.75) | EPHX1ALDH1A1HTTEPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815951-B2 | Inhibitors of epoxide hydrolases for the treatment of inflammation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-26 | — | — | US | disclosed |