Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690282 | 0.84 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL2339100 | 0.84 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL3253168 | 0.83 | NAPRT (0.74) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| Hydrochloric Acid SCHEMBL16238944 | 0.82 | NAPRT (0.67) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL48609 | 0.82 | NAPRT (1.00) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL15515595 | 0.82 | NAPRT (0.71) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL29430342 | 0.82 | NAPRT (1.00) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL794394 | 0.80 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| SCHEMBL8603768 | 0.80 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL | |
| Potassium Ion SCHEMBL17653885 | 0.80 | NAPRT (0.69) | NAPRTCYP1A2CYP3A4CYP2C9RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816122-B2 | Prostratin analogs, bryostatin analogs, prodrugs, synthetic methods, and methods of use | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-08-26 | — | — | US | disclosed |
| US-7964624-B1 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-06-21 | — | — | US | disclosed |