Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062656 | 1.00 | CYP3A4 (0.49) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL15976269 | 0.96 | CYP3A4 (0.46) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL12755497 | 0.90 | DPP4 (0.48) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL13014840 | 0.90 | DPP4 (0.48) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL12824174 | 0.88 | DPP4 (0.52) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL5995215 | 0.87 | CYP3A4 (0.47) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL5992389 | 0.87 | CYP3A4 (0.48) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL888989 | 0.86 | DPP4 (0.45) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL12824316 | 0.86 | DPP4 (0.45) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 | |
| SCHEMBL12755515 | 0.86 | DPP4 (0.44) | CYP3A4CYP2C9NR1I2ABCB11OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815928-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2014-08-26 | — | — | US | disclosed |