⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461904 | 0.74 | — | — | |
| SCHEMBL19687780 | 0.71 | — | — | |
| SCHEMBL10514508 | 0.64 | TSHR (0.36) | — | |
| SCHEMBL9011785 | 0.61 | TSHR (0.33) | — | |
| SCHEMBL22273256 | 0.61 | — | — | |
| SCHEMBL2940586 | 0.61 | — | — | |
| SCHEMBL26011721 | 0.61 | — | — | |
| SCHEMBL987315 | 0.59 | TSHR (0.31) | — | |
| SCHEMBL83729 | 0.58 | — | — | |
| SCHEMBL19443217 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150064130-A1 | PROTEIN-POLYMER-DRUG CONJUGATES | MERSANA THERAPEUTICS, INC. | 2015-03-05 | — | — | US | disclosed |
| US-8815226-B2 | Protein-polymer-drug conjugates | MERSANA THERAPEUTICS, INC. (US) | 2014-08-26 | — | — | US | disclosed |