Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246266 | 0.78 | CYP3A4 (0.54) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL21153968 | 0.78 | MCHR1 (0.53) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL2248886 | 0.77 | CYP3A4 (0.53) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL15977193 | 0.77 | MCHR1 (0.54) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL30569677 | 0.77 | HTR2A (0.51) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL4790752 | 0.74 | MCHR1 (0.41) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL12129433 | 0.73 | APP (0.44) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL12128972 | 0.73 | APP (0.49) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL21088048 | 0.72 | MCHR1 (0.53) | MCHR1HTR2AHTR2CKDM4EALOX15 | |
| SCHEMBL21088049 | 0.72 | HTR2A (0.50) | MCHR1HTR2AHTR2CKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476680-B1 | (1-Azinone)-Substituted Pyridoindoles | ALBANY MOLECULAR RES INC (US) | 2014-08-27 | — | — | EP | disclosed |