SCHEMBL15977217

SCHEMBL15977217

C=CN1CCc2c(n(C)c3cc(-n4ccc(OCc5ccccc5)cc4=O)ccc23)C1C

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.68
CYP3A4 P08684 3/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476107 0.90 MCHR1 (0.74) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3477615 0.89 MCHR1 (0.73) MCHR1CYP3A4
SCHEMBL11425459 0.81 MCHR1 (0.70) MCHR1CYP3A4
SCHEMBL94121 0.81 MCHR1 (1.00) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3478081 0.80 MCHR1 (0.69) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL132638 0.80 MCHR1 (0.98) MCHR1CYP3A4
SCHEMBL94216 0.80 MCHR1 (1.00) MCHR1CYP3A4
SCHEMBL94365 0.79 MCHR1 (1.00) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL135867 0.79 MCHR1 (0.98) MCHR1CYP3A4
SCHEMBL1005412 0.79 MCHR1 (1.00) MCHR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2476680-B1 (1-Azinone)-Substituted Pyridoindoles ALBANY MOLECULAR RES INC (US) 2014-08-27 EP disclosed