SCHEMBL15977271

SCHEMBL15977271

CCn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CN(CC(=O)N1CCCC1)CC2

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.65
CYP3A4 P08684 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477924 0.92 MCHR1 (0.77) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3477411 0.91 MCHR1 (0.76) MCHR1CYP3A4
SCHEMBL3478351 0.88 MCHR1 (0.73) MCHR1CYP3A4
SCHEMBL11424246 0.85 MCHR1 (0.81) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3476551 0.84 MCHR1 (0.79) MCHR1CYP3A4
SCHEMBL15977245 0.84 MCHR1 (0.79) MCHR1CYP3A4
SCHEMBL3478118 0.83 MCHR1 (0.68) MCHR1CYP3A4
SCHEMBL15889560 0.82 MCHR1 (0.69) MCHR1CYP3A4
SCHEMBL11426090 0.82 MCHR1 (0.73) MCHR1CYP3A4
Hydrochloric Acid SCHEMBL3477516 0.81 MCHR1 (0.72) MCHR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2476680-B1 (1-Azinone)-Substituted Pyridoindoles ALBANY MOLECULAR RES INC (US) 2014-08-27 EP disclosed