SCHEMBL15977409

SCHEMBL15977409

c1ccc2cc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5ncncn5)ccc34)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
MAPK9 P45984 2/20 0.40
MAPK10 P53779 2/20 0.40
CYP11B1 P15538 3/20 0.38
CYP11B2 P19099 3/20 0.38
CYP17A1 P05093 1/20 0.38
CYP19A1 P11511 1/20 0.38
IKBKB O14920 1/20 0.36
HTR2B P41595 1/20 0.36
HTR5A P47898 1/20 0.36
CYP1A2 P05177 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GSTP1 P09211 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977787 0.94 KDM4E (0.41) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL18431646 0.93 MEN1 (0.40) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15977799 0.90 CYP2A6 (0.41) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15977691 0.89 KDM4E (0.44) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15977453 0.88 SMN1; SMN2 (0.42) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15978580 0.87 ESR1 (0.39) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15977423 0.86 KDM4E (0.38) KDM4EMAPK9MAPK10CYP11B1CYP11B2
SCHEMBL15977630 0.85 IKBKB (0.41) KDM4ECYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL15977411 0.85 SMN1; SMN2 (0.43) KDM4ECYP11B1CYP11B2CYP17A1CYP19A1
SCHEMBL15977653 0.85 CYP11B1 (0.41) KDM4EMAPK9MAPK10CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed