Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978659 | 0.92 | ELANE (0.43) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL7347260 | 0.92 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL9075150 | 0.92 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL9075147 | 0.92 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL15978652 | 0.91 | POLB (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL16256989 | 0.91 | ELANE (0.49) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL29510702 | 0.91 | ELANE (0.49) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL2569236 | 0.89 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL2569233 | 0.89 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 | |
| SCHEMBL7408542 | 0.89 | ELANE (0.45) | ELANELMNAPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014127747-A1 | DPP-IV-INHIBITING COMPOUNDS AND INTERMEDIATES THEREOF | 成都先导药物开发有限公司 (CN) | 2014-08-28 | — | — | WO | disclosed |