SCHEMBL15978749

SCHEMBL15978749

c1ccc(-c2nc3ccccc3n2-c2ccc(-c3cc4ccc5cc(-c6c7ccccc7cc7ccccc67)cc6ccc(c3)c4c56)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
GRIA1 P42261 1/20 0.46
CACNG8 Q8WXS5 1/20 0.46
CACNG2 Q9Y698 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSP90AA1 P07900 1/20 0.44
MAPT P10636 1/20 0.44
PTGS2 P35354 1/20 0.42
ALDH1A1 P00352 7/20 0.42
HDAC1 Q13547 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPK10 P53779 3/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25769064 0.91 ESR1 (0.60) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL24813299 0.90 ESR1 (0.54) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25769014 0.89 ESR1 (0.62) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15978824 0.89 ESR2 (0.65) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL24573509 0.89 ESR1 (0.50) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15978744 0.88 ESR2 (0.60) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL15978756 0.87 ESR1 (0.56) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25668040 0.86 ESR1 (0.49) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL25668140 0.86 ESR1 (0.60) ESR1ESR2GRIA1CACNG8CACNG2
SCHEMBL18999314 0.86 ESR1 (0.60) ESR1ESR2GRIA1CACNG8CACNG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10193072-B2 Pyrene-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-29 US disclosed
US-20140239269-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-28 US disclosed
US-20140239269-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-28 US disclosed