Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3086239 | 1.00 | PARP1 (0.61) | PARP1 | |
| SCHEMBL3073345 | 1.00 | PARP1 (0.61) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3079654 | 0.96 | PARP1 (0.57) | PARP1 | |
| SCHEMBL3082284 | 0.95 | PARP1 (0.62) | PARP1 | |
| SCHEMBL15988317 | 0.95 | PARP1 (0.62) | PARP1 | |
| SCHEMBL3075525 | 0.95 | PARP1 (0.62) | PARP1 | |
| SCHEMBL15988452 | 0.95 | PARP1 (0.63) | PARP1 | |
| SCHEMBL15988309 | 0.92 | PARP1 (0.54) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3078866 | 0.91 | PARP1 (0.57) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL3063656 | 0.91 | PARP1 (0.58) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220073-B1 | PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS | MSD ITALIA SRL (IT) | 2014-09-03 | — | — | EP | claimed |